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Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Prime members enjoy FREE Delivery and exclusive access to music, movies, TV shows, original audio series, and Kindle books. Les larmes artificielles enrichies en lipides REFRESH OPTIVE AVANCÉ MD protègent les larmes que vous produisez naturellement pour empêcher leur évaporation. The cost for Refresh Optive Advanced ophthalmic solution is around $20 for a supply of 10 milliliters, depending on the pharmacy you visit. Pricing Drug Information. Price Drop Below* At any Pharmacy near 77381. Update your shipping location. This is an import. Refresh Optive Advanced offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. It retails for $11.49, but you'll only have to pay $8.49. 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